持续近两个多月的新型冠状病毒感染的肺炎疫情牵动着每一个人的心，为了打赢这场疫情防控狙击战，搞清致病机理，研发抗病毒药物和疫苗刻不容缓。Jena bioscience品牌有丰富的抗病毒核苷酸/核苷酸类似物，助力抗病毒药物研发。
抗病毒核苷及核苷酸类似物主要有:
抗病毒核苷/核苷酸类似物可以通过抑制病毒复制的几个关键过程来抑制病毒繁殖，它们通过与天然的dNTP/NTP竞争结合到新的病毒核酸中，从而导致链终止或者诱变。在细胞培养实验中，可以用抗病毒核苷酸的非磷酸化核苷变体，这种核苷酸在细胞内被多种病毒和/或宿主激酶激活，从而发挥(tri)磷酸化形式的抗病毒作用。
热销抗病毒核苷/核苷酸类似物：
品牌
货号
品名
规格
Jena Bioscience
NU-1605S
3TCMP
10 μl (10 mM)
Jena Bioscience
NU-1605L
3TCMP
5 x 10 μl (10 mM)
Jena Bioscience
NU-1606S
3TCTP
5 μl (10 mM)
Jena Bioscience
NU-1606L
3TCTP
5 x 5 μl (10 mM)
Jena Bioscience
NU-1603S
d4TMP
20 μl (10 mM)
Jena Bioscience
NU-1603L
d4TMP
5 x 20 μl (10 mM)
Jena Bioscience
NU-1601S
AzTMP
20 μl (10 mM)
Jena Bioscience
NU-1601L
AzTMP
5 x 20 μl (10 mM)
Jena Bioscience
NU-989S
AzTTP
10 μl (100 mM)
Jena Bioscience
NU-989L
AzTTP
5 x 10 μl (100 mM)
Jena Bioscience
NU-875
ara-Adenosine-5'-monophosphate (ara-AMP)
2 mg
Jena Bioscience
NU-1111S
50 μl (10 mM)
Jena Bioscience
NU-1111L
ara-Adenosine-5'-triphosphate (ara-ATP)
5 x 50 μl (10 mM)
Jena Bioscience
NU-876
Acyclovir-5'-monophosphate
2 mg
Jena Bioscience
NU-877
Acyclovir-5'-triphosphate
2 mg
Jena Bioscience
NU-021-2
Ribavirin-5'-monophosphate
2 mg
Jena Bioscience
NU-1105S
20 μl (10 mM)
Jena Bioscience
NU-1105L
Ribavirin-triphosphate
5 x 20 μl (10 mM)
Jena Bioscience
N-DN-8234-100
β-L-2'-Deoxythymidine
100 mg
Jena Bioscience
NU-896S
10 μl (100 mM)
Jena Bioscience
NU-896L
6-Aza-UTP
5 x 10 μl (100 mM)
Jena Bioscience
NU-974
Tenofovir
100 mg
Jena Bioscience
NU-975
Tenofovir-diphosphate
1 mg
Jena Bioscience
NU-989S
10 μl (100 mM)
Jena Bioscience
NU-989L
AzTTP
5 x 10 μl (100 mM)
Jena Bioscience
NU-275S
10 μl
Jena Bioscience
NU-275L
Ganciclovir-triphosphate
5 x 10 μl
西美杰是Jena bioscience中国总代理，为用户提供完善的技术与售后服务。如对产品感兴趣欢迎拨打西美杰客服热线400-050-4006了解详细信息。西美杰会更好的协助科研工作者的实验工作，支持全国战“疫”，早日战胜病毒。武汉加油！中国加油！
参考文献：
1] Huang at al. (2011) Effect of reverse transcriptase inhibitors on Line-1 and Ty1 reverse transcriptase activities and on LINE-1 retrotransposition. BMC Biochemistry 12:18.
[2] Vaccaro at al. (1999) Mechanism of Inhibition of the Human Immunodeficiency Virus Type 1 Reverse Transcriptase by d4TTP: an Equivalent Incorporation Efficiency Relative to the Natural Substrate dTTP. Antimicrob. Agents Chemother. 44 (1):217.
[3] Jaju at al. (1995) Human immunodeficiency virus type 1 reverse transcriptase. 3'-Azidodeoxythymidine 5'-triphosphate inhibition indicates two-step binding for template-primer. J. Biol. Chem. 270 (17):9740.
[4] Furmann at al. (1979) Inhibition of Herpes Simplex Virus-Induced DNA Polymerase Activity and Viral DNA Replication by 9-(2-Hydroxyethoxymethyl)guanine and Its Triphosphate. J. Virol. 29 (2):154.
[5] Muller at al. (1977) Inhibition of Herpesvirus DNA synthesis by 9-O-D-Arabinofuranosyladenine in cellular and cell-free systems. Ann. N.Y. Acad. Sci. 284:34.
[6] Crotty at al. (2000) The broad-spectrum antiviral ribonucleoside ribavirin is an RNA virus mutagen. Nature Medicine 6 (12):1375.
[7] Ray at al. (2009) Metabolism of antiviral nucleosides and nucleotides. In: Antiviral Research: Strategies in antiviral drug discovery (LaFemina). ASM Press.
[8] Simons at al. (2005) Recent Advances in Antiviral Nucleoside and Nucleotide Therapeutics. Current Topics in Medicinal Chemistry 5:1191.
京公网安备 11010802028692号 
北京客服1